Ceruloplasmin Antikörper (AA 20-259) (APC)

Produktnummer ABIN7978228

Der Kaninchen Polyklonal anti-Ceruloplasmin Antikörper wird verwendet zum Nachweis von Ceruloplasmin in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Ceruloplasmin Antikörper (AA 20-259) (APC) (ABIN7978228)

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ceruloplasmin Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Ceruloplasmin Antikörper (APC)

Bindungsspezifität: AA 20-259

Verwendungszweck: Anti-Ceruloplasmin/CP Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8%,79.6% amino acid (aa) sequence identity with mouse,rat Ceruloplasmin,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8% and 79.6% amino acid (aa) sequence identity with mouse and rat Ceruloplasmin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Ceruloplasmin

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Andere Bezeichnung: CP

Hintergrund:

Background: Ceruloplasmin  (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Gene Full Name: ceruloplasmin

Gen-ID: 1356

UniProt: P00450

Pathways: Transition Metal Ion Homeostasis