CD3D Antikörper (AA 22-171) (Fluoro488)

Produktnummer ABIN7976792

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-CD3D Antikörper (ABIN7976792) detektiert spezifisch CD3D in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD3D Antikörper (AA 22-171) (Fluoro488) (ABIN7976792)

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3D Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD3D Antikörper (Fluoro488)

Bindungsspezifität: AA 22-171

Verwendungszweck: Anti-CD3D Antibody Fluoro488 Conjugated

Homologie: Human CD3D shares 66%,70.7% amino acid (aa) sequence identity with mouse,rat CD3D,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CD3D recombinant protein (Position: F22-K171). Human CD3D shares 66% and 70.7% amino acid (aa) sequence identity with mouse and rat CD3D, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CD3D

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Andere Bezeichnung: CD3D

Hintergrund:

Background: T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene. The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Gene Full Name: CD3 delta subunit of T-cell receptor complex

Gen-ID: 915

UniProt: P04234

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events