CD3D Antikörper (AA 22-105)

Produktnummer ABIN5684129

Produktdetails anti-CD3D Antikörper

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Bindungsspezifität: AA 22-105

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD3D (AA: extra 22-105) expressed in E. coli.

Klon: 8D11D5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu CD3D

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Andere Bezeichnung: CD3D (CD3D Produkte)

Synonyme: CD3-DELTA antikoerper, T3D antikoerper, CD3 antikoerper, T3d antikoerper, CD3d molecule antikoerper, CD3 antigen, delta polypeptide antikoerper, CD3D antikoerper, Cd3d antikoerper

Hintergrund:

Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Aliases: T3D, IMD19, CD3-DELTA

Molekulargewicht: 18.9 kDa

Gen-ID: 915

HGNC: 10666

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events