CD38 Antikörper (C-Term) (HRP)

Produktnummer ABIN7976785

Der Kaninchen Polyklonal anti-CD38 Antikörper wird verwendet zum Nachweis von CD38 in Proben von Maus und Ratte. Er wurde validiert für IHC, WB und ELISA.

Kurzübersicht für CD38 Antikörper (C-Term) (HRP) (ABIN7976785)

Target: CD38

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD38 Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Produktdetails anti-CD38 Antikörper (HRP)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Cd38 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cd38, which shares 81.8% and 86.7% amino acid (aa) sequence identity with human and rat Cd38, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CD38

Target: CD38

Hintergrund:

Background: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

Gene Full Name: CD38 antigen

Gen-ID: 12494

UniProt: P56528