CD2 Antikörper (AA 23-203) (Fluoro488)

Produktnummer ABIN7976407

Der Kaninchen Polyklonal anti-CD2 Antikörper wird verwendet zum Nachweis von CD2 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für CD2 Antikörper (AA 23-203) (Fluoro488) (ABIN7976407)

Target: CD2

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD2 Antikörper (Fluoro488)

Bindungsspezifität: AA 23-203

Verwendungszweck: Anti-CD2/CD2 Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse CD2 recombinant protein (Position: R23-S203). Mouse CD2 shares 49.7%,73.3% amino acid (aa) sequence identity with human,rat CD2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse CD2 recombinant protein (Position: R23-S203). Mouse CD2 shares 49.7% and 73.3% amino acid (aa) sequence identity with human and rat CD2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CD2

Target: CD2

Andere Bezeichnung: Cd2

Hintergrund:

Background: CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. Monoclonal antibodies ed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. CD2 is one of the earliest T-cell markers, being present on more than 95 % of thymocytes. Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily, it possesses two immunoglobulin-like domains in its extracellular portion. The localization of CD2 to 1p13 is established by in situ hybridization. CD2 interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. With the use of transgenic mice, such an LCR is identified within the 3-prime flanking region of the human CD2 gene.

Gene Full Name: CD2 antigen

Gen-ID: 914

UniProt: P08920