Cathepsin D Antikörper (AA 201-412) (APC)

Produktnummer ABIN7975840

Der Kaninchen Polyklonal anti-Cathepsin D Antikörper wird verwendet zum Nachweis von Cathepsin D in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Cathepsin D Antikörper (AA 201-412) (APC) (ABIN7975840)

Target: Cathepsin D (CTSD)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin D Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Cathepsin D Antikörper (APC)

Bindungsspezifität: AA 201-412

Verwendungszweck: Anti-Cathepsin D/CTSD Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human Cathepsin D shares 84.4%,84% amino acid (aa) sequence identity with mouse,rat Cathepsin D,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human < a href=https://www.bosterbio.com/anti-cathepsin-d-picoband-trade-antibody-a01361-boster.html>Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: CTSD

Hintergrund:

Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

Gene Full Name: cathepsin D

Gen-ID: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism