CREB3 Antikörper (AA 1-352) (FITC)

Produktnummer ABIN7974495

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CREB3 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CREB3 Antikörper (AA 1-352) (FITC) (ABIN7974495)

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREB3 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CREB3 Antikörper (FITC)

Bindungsspezifität: AA 1-352

Verwendungszweck: Anti-CREB3 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CREB3 recombinant protein (Position: M1-K352). Human CREB3 shares 67.1% amino acid (aa) sequence identity with mouse CREB3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CREB3

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Andere Bezeichnung: CREB3

Hintergrund:

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Gene Full Name: cAMP responsive element binding protein 3

Gen-ID: 10488

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response