CAMLG Antikörper (Middle Region) (HRP)

Produktnummer ABIN7974122

Der HRP-konjugierte Kaninchen Polyklonal anti-CAMLG Antikörper (ABIN7974122) detektiert spezifisch CAMLG in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CAMLG Antikörper (Middle Region) (HRP) (ABIN7974122)

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMLG Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CAMLG Antikörper (HRP)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-CAMLG Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CAMLG shares 91.7%,95.7% amino acid (aa) sequence identity with mouse,rat CAMLG,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CAMLG. Human CAMLG shares 91.7% and 95.7% amino acid (aa) sequence identity with mouse and rat CAMLG, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CAMLG

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Andere Bezeichnung: CAMLG

Hintergrund:

Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Gene Full Name: calcium modulating ligand

Gen-ID: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway