Butyrylcholinesterase Antikörper (AA 263-571) (Cy3)

Produktnummer ABIN7973500

Der Kaninchen Polyklonal anti-Butyrylcholinesterase Antikörper wird verwendet zum Nachweis von Butyrylcholinesterase in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für Butyrylcholinesterase Antikörper (AA 263-571) (Cy3) (ABIN7973500)

Target: Butyrylcholinesterase (BCHE)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Butyrylcholinesterase Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Butyrylcholinesterase Antikörper (Cy3)

Bindungsspezifität: AA 263-571

Verwendungszweck: Anti-Butyrylcholinesterase/BCHE Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Andere Bezeichnung: Bche

Hintergrund:

Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Gene Full Name: butyrylcholinesterase

Sequence Similarities: Contains 1 CARD domain.

Gen-ID: 12038

UniProt: Q03311

Pathways: Peptide Hormone Metabolism