beta-2 Microglobulin Antikörper (AA 22-119) (Fluoro550)
Kurzübersicht für beta-2 Microglobulin Antikörper (AA 22-119) (Fluoro550) (ABIN7972611)
Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 22-119
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Verwendungszweck
- Anti-Beta 2 Microglobulin B2M Antibody (monoclonal, 2H10) Fluoro550 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Homologie
- Human Beta 2 Microglobulin shares 69.4%,74.5% amino acid (aa) sequence identity with mouse,rat Beta 2 Microglobulin,respectively.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Beta 2 Microglobulin recombinant protein (Position: Q22-M119). Human Beta 2 Microglobulin shares 69.4% and 74.5% amino acid (aa) sequence identity with mouse and rat Beta 2 Microglobulin, respectively.
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Isotyp
- IgG2b
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Andere Bezeichnung
- B2M
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Hintergrund
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Background: Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Gene Full Name: beta-2-microglobulin
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Gen-ID
- 567
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UniProt
- P61769
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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