BCL6 Antikörper (AA 28-336) (Cy3)
Kurzübersicht für BCL6 Antikörper (AA 28-336) (Cy3) (ABIN7971913)
Target
Alle BCL6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 28-336
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Verwendungszweck
- Anti-BCL6 Antibody Cy3 Conjugated
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Homologie
- Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human BCL6 recombinant protein (Position: R28-K336). Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, 1-3 μg/1x106 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Andere Bezeichnung
- BCL6
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Hintergrund
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Background: Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Gene Full Name: BCL6 transcription repressor
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Gen-ID
- 604
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UniProt
- P41182
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Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Target
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