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BCL6 Antikörper (AA 28-336) (Cy3)

Der Kaninchen Polyklonal anti-BCL6 Antikörper wird verwendet zum Nachweis von BCL6 in Proben von Human. Er wurde validiert für FACS.
Produktnummer ABIN7971913
720,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen

Kurzübersicht für BCL6 Antikörper (AA 28-336) (Cy3) (ABIN7971913)

Target

Alle BCL6 Antikörper anzeigen
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reaktivität

  • 231
  • 63
  • 25
  • 9
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 144
  • 85
  • 2
Kaninchen

Klonalität

  • 147
  • 84
Polyklonal

Konjugat

  • 120
  • 16
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser BCL6 Antikörper ist konjugiert mit Cy3

Applikation

  • 100
  • 96
  • 59
  • 49
  • 43
  • 39
  • 27
  • 23
  • 18
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • Bindungsspezifität

    • 69
    • 15
    • 14
    • 12
    • 12
    • 11
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-336

    Verwendungszweck

    Anti-BCL6 Antibody Cy3 Conjugated

    Homologie

    Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human BCL6 recombinant protein (Position: R28-K336). Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.

    Isotyp

    IgG
  • Applikationshinweise

    Flow Cytometry, 1-3 μg/1x106 cells

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    Haltbarkeit

    12 months
  • Target

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    Andere Bezeichnung

    BCL6

    Hintergrund

    Background: Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    Gene Full Name: BCL6 transcription repressor

    Gen-ID

    604

    UniProt

    P41182

    Pathways

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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