Liver Arginase Antikörper (AA 25-183) (PE)

Produktnummer ABIN7969925

Der PE-konjugierte Maus Monoklonal anti-Liver Arginase Antikörper (Klon 2B12) (ABIN7969925) detektiert spezifisch Liver Arginase in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Affe.

Kurzübersicht für Liver Arginase Antikörper (AA 25-183) (PE) (ABIN7969925)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Liver Arginase Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 2B12

Produktdetails anti-Liver Arginase Antikörper (PE)

Bindungsspezifität: AA 25-183

Verwendungszweck: Anti-liver Arginase/ARG1 Antibody (monoclonal, 2B12) PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human liver Arginase/ARG1 recombinant protein (Position: E25-D183).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: ARG1

Hintergrund:

Background: ARG1 (arginase, live) is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded byARG1, referred to as the liver, or A-I, isoform, contributes 98 % of the arginase activity in liver but is also present in red cells. Using a rat liverARG1cDNA clone to probe a human liver cDNA library,Haraguchi et al. (1987)isolated and characterized a cDNA corresponding to theARG1gene.The ARG1 gene is mapped on 6q23.2 and the arginase gene contains 8 exons. By immunologic studies, 90 % of the arginase in red blood cell and liver was precipitated by the antibody, whereas only 50 % of the arginase in kidney, brain, and the gastrointestinal tract reacted with it. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: arginase 1

Gen-ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin