APOE Antikörper (AA 55-294) (Fluoro550)

Produktnummer ABIN7969447

Der Kaninchen Polyklonal anti-APOE Antikörper wird verwendet zum Nachweis von APOE in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für APOE Antikörper (AA 55-294) (Fluoro550) (ABIN7969447)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-APOE Antikörper (Fluoro550)

Bindungsspezifität: AA 55-294

Verwendungszweck: Anti-Apolipoprotein E/APOE Antibody Fluoro550 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse Apolipoprotein E shares 75%,94.6% amino acid (aa) sequence identity with human,rat Apolipoprotein E,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: Apoe

Hintergrund:

Background: APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

Gene Full Name: apolipoprotein E

Gen-ID: 11816

UniProt: P08226

Pathways: Regulation of Cell Size, Lipid Metabolism