APOE Antikörper (AA 19-317) (Fluoro550)

Produktnummer ABIN7969436

Der Fluoro550-konjugierte Kaninchen Polyklonal anti-APOE Antikörper (ABIN7969436) detektiert spezifisch APOE in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für APOE Antikörper (AA 19-317) (Fluoro550) (ABIN7969436)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-APOE Antikörper (Fluoro550)

Bindungsspezifität: AA 19-317

Verwendungszweck: Anti-Apolipoprotein E/APOE Antibody Fluoro550 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Apolipoprotein E shares 73%,72% amino acid (aa) sequence identity with mouse,rat Apolipoprotein E,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Apolipoprotein E recombinant protein (Position: K19-H317). Human Apolipoprotein E shares 73% and 72% amino acid (aa) sequence identity with mouse and rat Apolipoprotein E, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: APOE

Hintergrund:

Background: APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

Gene Full Name: apolipoprotein E

Sequence Similarities: Belongs to the apolipoprotein A1/A4/E family.

Gen-ID: 348

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism