Angiopoietin 1 Antikörper (AA 16-350) (Fluoro647)

Produktnummer ABIN7968474

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-Angiopoietin 1 Antikörper (ABIN7968474) detektiert spezifisch Angiopoietin 1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Angiopoietin 1 Antikörper (AA 16-350) (Fluoro647) (ABIN7968474)

Target: Angiopoietin 1 (ANGPT1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 1 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Angiopoietin 1 Antikörper (Fluoro647)

Bindungsspezifität: AA 16-350

Verwendungszweck: Anti-Angiopoietin 1/ANGPT1 Antibody Fluoro647 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse,rat Angiopoietin 1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Angiopoietin 1 recombinant protein (Position: H16-N350). Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse and rat Angiopoietin 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: ANGPT1

Hintergrund:

Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Gene Full Name: angiopoietin 1

Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

Gen-ID: 284

UniProt: Q15389

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process