APCS Antikörper (AA 21-224)

Produktnummer ABIN7968332

Der Kaninchen Polyklonal anti-APCS Antikörper wird verwendet zum Nachweis von APCS in Proben von Maus und Ratte. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für APCS Antikörper (AA 21-224) (ABIN7968332)

Target: APCS (Amyloid P Component, Serum (APCS))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APCS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Güteklasse: Carrier-free

Produktdetails anti-APCS Antikörper

Bindungsspezifität: AA 21-224

Verwendungszweck: Anti-Serum Amyloid P/APCS Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse Serum Amyloid P shares 70%,80% amino acid (aa) sequences identity with human,rat Serum Amyloid P,respectively.

Produktmerkmale: Anti-Serum Amyloid P/APCS Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Serum Amyloid P recombinant protein (Position: Q21-D224). Mouse Serum Amyloid P shares 70% and 80% amino acid (aa) sequences identity with human and rat Serum Amyloid P, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, 0.1-0.5 μg/mL, -Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, RatWestern blot, 0.1-0.5 μg/mL, Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Andere Bezeichnung: APCS

Hintergrund:

Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called amyloid. It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Gene Full Name: amyloid P component, serum

Sequence Similarities: Belongs to the pentaxin family.

Molekulargewicht: 25-29 kDa

Gen-ID: 20219

UniProt: P12246