Amphiregulin Antikörper (AA 100-191)

Produktnummer ABIN7968145

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Amphiregulin in WB, IHC, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für Amphiregulin Antikörper (AA 100-191) (ABIN7968145)

Target: Amphiregulin (AREG)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amphiregulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-Amphiregulin Antikörper

Bindungsspezifität: AA 100-191

Verwendungszweck: Anti-Amphiregulin/Areg Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Amphiregulin/Areg Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Amphiregulin recombinant protein (Position:V100-K191).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Rat ELISA (Cap), 1-5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Amphiregulin

Target: Amphiregulin (AREG)

Andere Bezeichnung: Areg

Hintergrund:

Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

Gene Full Name: amphiregulin

Molekulargewicht: 45 kDa

Gen-ID: 11839

UniProt: P31955

Pathways: RTK Signalweg, EGFR Signaling Pathway