AGRN Antikörper (AA 1864-2068) (HRP)

Produktnummer ABIN7967228

Der Kaninchen Polyklonal anti-AGRN Antikörper wird verwendet zum Nachweis von AGRN in Proben von Human, Ratte und Maus. Er wurde validiert für IHC, WB und ELISA.

Kurzübersicht für AGRN Antikörper (AA 1864-2068) (HRP) (ABIN7967228)

Target: AGRN (Agrin (AGRN))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGRN Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Produktdetails anti-AGRN Antikörper (HRP)

Bindungsspezifität: AA 1864-2068

Verwendungszweck: Anti-Agrin/AGRN Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Agrin/AGRN recombinant protein (Position: S1864-P2068).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AGRN

Target: AGRN (Agrin (AGRN))

Andere Bezeichnung: AGRN

Hintergrund:

Background: Agrin is a protein that in humans is encoded by the AGRN gene. It is mapped to 1p36.33. This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: agrin

Gen-ID: 375790

UniProt: O00468

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development