RAGE Antikörper (AA 24-320)

Produktnummer ABIN7967122

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAGE in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für RAGE Antikörper (AA 24-320) (ABIN7967122)

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails anti-RAGE Antikörper

Bindungsspezifität: AA 24-320

Verwendungszweck: Anti-Ager Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ager Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Ager recombinant protein (Position: Q24-E320).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Andere Bezeichnung: Ager

Hintergrund:

Background: Enables S100 protein binding activity, advanced glycation end-product binding activity, and heparin binding activity. Involved in several processes, including cellular response to amyloid-beta, negative regulation of long-term synaptic potentiation, and positive regulation of cytokine production. Acts upstream of or within several processes, including induction of positive chemotaxis, negative regulation of advanced glycation end-product receptor activity, and positive regulation of macromolecule metabolic process. Located in extracellular space and plasma membrane. Is expressed in several structures, including alimentary system, brain, genitourinary system, hemolymphoid system gland, and lung. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), cardiovascular system disease (multiple), cystic fibrosis, kidney failure (multiple), and lupus nephritis. Orthologous to human AGER (advanced glycosylation end-product specific receptor).

Gene Full Name: advanced glycosylation end product-specific receptor

Molekulargewicht: 43 kDa, 58 kDa

Gen-ID: 11596

UniProt: Q62151

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine