ABI1 Antikörper (C-Term) (Cy3)

Produktnummer ABIN7965342

Der Cy3-konjugierte Kaninchen Polyklonal anti-ABI1 Antikörper (ABIN7965342) detektiert spezifisch ABI1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für ABI1 Antikörper (C-Term) (Cy3) (ABIN7965342)

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ABI1 Antikörper (Cy3)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-SSH3BP1/ABI1 Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related rat,mouse sequences by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ABI1, different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: ABI1

Hintergrund:

Background: ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

Gene Full Name: abl interactor 1

Sequence Similarities: Contains 12 fibronectin type-I domains.

Gen-ID: 10006

UniProt: Q8IZP0

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling