Rekombinanter SMAD1 Antikörper (pSer195)

Produktnummer ABIN7938495

Der Kaninchen Monoklonal anti-SMAD1 Antikörper (Klon 1K6) (ABIN7938495) detektiert spezifisch SMAD1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter SMAD1 Antikörper (pSer195) (ABIN7938495)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SMAD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1K6

Produktdetails anti-SMAD1 Antikörper

Bindungsspezifität: pSer195

Verwendungszweck: SMAD1 phospho Ser195 (rAb), 100 μl (Clone 1K6)

Aufreinigung: Protein A Chromatography

Immunogen: This information is proprietary to Active Motif and/or its suppliers.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:10000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Andere Bezeichnung: SMAD1

Hintergrund: SMAD family member 1 (SMAD1) have been involved in metastatic progression of many cancer types. SMAD1) can be induced by many tumor-stimulating cytokines such as the bone morphogenetic protein 2 (BMP2) and TNFa and plays important roles in cell invasion and metastasis. BMP2 signaling is initiated by binding to its specific receptors, which leads to in the phosphorylation and nuclear translocation of Smad1. Translocated SMAD1) then modulates the expression of downstream osteogenic genes.

Molekulargewicht: 52 kDa

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development