Rekombinanter RUNX2 Antikörper

Produktnummer ABIN7938452

Der Kaninchen Monoklonal anti-RUNX2 Antikörper wird verwendet zum Nachweis von RUNX2 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für Rekombinanter RUNX2 Antikörper (ABIN7938452)

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RUNX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1G5

Produktdetails anti-RUNX2 Antikörper

Verwendungszweck: RUNX2 antibody (rAb), 100 μg (Clone 1G5)

Aufreinigung: Protein A Chromatography

Immunogen: This information is proprietary to Active Motif and/or its suppliers.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:10000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu RUNX2

Target: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Andere Bezeichnung: RUNX2

Hintergrund:

Background_Plain: RUNX2, also named as AML3, CBFA1, OSF2 and PEBP2A, is a Transcription factor which involved in osteoblastic differentiation and skeletal morphogenesis. It is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters By similarity. RUNX2 inhibits MYST4-dependent transcriptional activation.

Aliases: Runt-related transcription factor 2

Molekulargewicht: 57 kDa

NCBI Accession: NM_004348