KDM2B Antikörper

Produktnummer ABIN7938317

Der Maus Monoklonal anti-KDM2B Antikörper wird verwendet zum Nachweis von KDM2B in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für KDM2B Antikörper (ABIN7938317)

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KDM2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: K2K842-13

Produktdetails anti-KDM2B Antikörper

Verwendungszweck: KDM2B antibody (mAb) (Clone K2K842-13)

Aufreinigung: Protein A Chromatography

Immunogen: This KDM2B antibody was raised against a peptide containing human lysine-specific demethylase 2B of isoform a.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5 - 2 μg/mL dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Andere Bezeichnung: KDM2B

Hintergrund:

Background_Plain: KDM2B (lysine (K)-specific demethylase 2B), also known as FBXL10 (F-box and leucine-rich repeat protein 10) is a histone demethylase that preferentially demethylates trimethylated lysine 4 (K4me3) and dimethylated lysine 36 (K36me2) of histone H3. KDM2B displays weak or no activity for mono- and trimethylated H3K36. KDM2B preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which results in inhibition of cell growth and proliferation. KDM2B may also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Aliases: FBXL10

Molekulargewicht: 100 kDa

NCBI Accession: NP_115979

Pathways: Tube Formation, Warburg Effekt