Histone H2A Antikörper (C-Term)

Produktnummer ABIN7938171

Der Ratte Monoklonal anti-Histone H2A Antikörper (Klon 1H11-11) (ABIN7938171) detektiert spezifisch Histone H2A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Histone H2A Antikörper (C-Term) (ABIN7938171)

Target: Histone H2A

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1H11-11

Produktdetails anti-Histone H2A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Histone H2A.Z.2.2 antibody (mAb) (Clone 1H11-11), sample

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against a peptide within the C-terminal region of human Histone H2A.Z.2.2.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu Histone H2A

Target: Histone H2A

Andere Bezeichnung: Histone H2A.

Hintergrund: Histone H2A.Z (H2A Histone Family, Member V) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may serve to allow H2A.Z to function as an insulator of chromatin domains. In the case of H2A.Z.2.2, this variant has been shown to be responsible for destabilization of the nucleosome through the chaperone complexes TIP60 and SRCAP.

Molekulargewicht: 12 kDa

NCBI Accession: NP_619541