Rekombinanter HDAC3 Antikörper

Produktnummer ABIN7938149

Der Kaninchen Monoklonal anti-HDAC3 Antikörper wird verwendet zum Nachweis von HDAC3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter HDAC3 Antikörper (ABIN7938149)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HDAC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 2N1

Produktdetails anti-HDAC3 Antikörper

Verwendungszweck: HDAC3 antibody (rAb), 100 μg (Clone 2N1)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against the HDAC3 fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:50000 dilution IHC: 1:50-1:500 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung: HDAC3

Hintergrund:

Background_Plain: Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the (amino groups of lysine's located near the amino termini of core histone proteins. At least 4 classes of HDAC were identified. HDAC3 is a class I HDAC. HDAC3 has histone deacetylase activity and may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. The gene encoding HDAC3 is regarded as a potential tumor suppressor gene.

Aliases: HD3, RPD3, RPD3-2

Molekulargewicht: 49 kDa

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development