Rekombinanter CDX2 Antikörper

Produktnummer ABIN7938091

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CDX2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter CDX2 Antikörper (ABIN7938091)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3J1

Produktdetails anti-CDX2 Antikörper

Verwendungszweck: CDX2 antibody (rAb), 100 μl (Clone 3J1)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against the CDX2 fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:5000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Andere Bezeichnung: CDX2

Hintergrund:

Background_Plain: CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and CDX2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.

Aliases: Caudal type homeobox 2

Molekulargewicht: 34 kDa

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance