Rekombinanter ATG7 Antikörper

Produktnummer ABIN7938048

Der Kaninchen Monoklonal anti-ATG7 Antikörper (Klon 2M8) (ABIN7938048) detektiert spezifisch ATG7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter ATG7 Antikörper (ABIN7938048)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ATG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 2M8

Produktdetails anti-ATG7 Antikörper

Verwendungszweck: ATG7 antibody (rAb), 100 μl (Clone 2M8)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against the ATG7 fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:10000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Andere Bezeichnung: ATG7

Hintergrund:

Background_Plain: ATG7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for ATG7 conjugation and autophagosome formation. ATG7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. The isoforms of ATG7 protein range from 68 kDa to 78 kDa.

Aliases: APG7-LIKE, APG7L, GSA7, autophagy related 7, SCAR31

Molekulargewicht: 78 kDa

Pathways: Response to Water Deprivation, Autophagie