SNRPE Antikörper (pSer444)

Produktnummer ABIN745358

Der Kaninchen Polyklonal anti-SNRPE Antikörper wird verwendet zum Nachweis von SNRPE in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IF (cc), IF (p) und IHC (fro).

Kurzübersicht für SNRPE Antikörper (pSer444) (ABIN745358)

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPE Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SNRPE Antikörper

Bindungsspezifität: pSer444

Homologie: Human,Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse B-Raf around the phosphorylation site of Ser444

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SNRPE

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Andere Bezeichnung: B-Raf

Hintergrund:

Synonyms: 94 kDa B raf protein, B raf 1, B Raf proto oncogene serine threonine protein kinase, BRAF 1, Braf, BRAF1, cRmil, MGC126806, MGC138284, Murine sarcoma viral v-raf oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, p94, RAFB 1, RAFB1, v raf murine sarcoma viral oncogene homolog B1, FLJ95109, BRAF_HUMAN.

Background: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.

Gen-ID: 109880

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C