Chromogranin A Antikörper

Produktnummer ABIN7884239

Der Kaninchen Polyklonal anti-Chromogranin A Antikörper (ABIN7884239) detektiert spezifisch Chromogranin A in IF und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Chromogranin A Antikörper (ABIN7884239)

Target: Chromogranin A (CHGA)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB)

Produktdetails anti-Chromogranin A Antikörper

Verwendungszweck: Catestatin Rabbit Polyclonal Antibody

Spezifität: The antibody recognizes the human Catestatin (CHGA352-372)

Aufreinigung: Purified

Immunogen: Catestatin 21AA fragment

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: If reconstituted with deionized water in 25 μL: WB: 1:4000, IF: 1:500. Optimal dilution has to be determined by the user.

Buffer: Lyophilised purified in PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: Catestatin

Hintergrund:

Cat7, Cst

Chromogranin-A is a secreted protein known as a ""prohormone"" which is found in endocrine cells and neurons and may be released upon stimulation. It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells. Catestatin is a 21 amino acids fragment (352 to 372) from Chromogranin A. It's a bioactive peptide that can stimulate histamine release from mast cells and it's an inhibitor of catecholamines release. Catestatin has been shown to also have cardiovascular functions and antimicrobial activity.

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling