Chromogranin A Antikörper (AA 87-252)

Produktnummer ABIN1724755

Produktdetails anti-Chromogranin A Antikörper

Target: Chromogranin A (CHGA)

Bindungsspezifität: AA 87-252

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CHGA (AA: 87-252 ) expressed in E. coli.

Klon: 1A6B6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:50, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Chromogranin A Antikörper (ABIN1724755)

Mergler, Skrzypski, Sassek, Pietrzak, Pucci, Wiedenmann, Strowski: "Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells." in: Cellular signalling, Vol. 24, Issue 1, pp. 233-46, (2011) (PubMed).

El Ali, Fichna, Piniewska, Kosowicz, Grzymis?awski: "Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease." in: Journal of endocrinological investigation, Vol. 33, Issue 3, pp. 186-91, (2010) (PubMed).

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: CHGA (CHGA Produkte)

Synonyme: CGA antikoerper, CG-ALPHA antikoerper, FSHA antikoerper, GPHA1 antikoerper, GPHa antikoerper, HCG antikoerper, LHA antikoerper, TSHA antikoerper, ChrA antikoerper, fj05f09 antikoerper, si:dkey-177p2.2 antikoerper, wu:fj05f09 antikoerper, zgc:101749 antikoerper, zgc:56075 antikoerper, CHGA antikoerper, cgA antikoerper, chga antikoerper, chromogranin A antikoerper, glycoprotein hormones, alpha polypeptide antikoerper, uncharacterized CHGA antikoerper, chromogranin A S homeolog antikoerper, CHGA antikoerper, CGA antikoerper, Chga antikoerper, chga antikoerper, chga.S antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. , ,

Aliases: CGA

Molekulargewicht: 50.7 kDa

Gen-ID: 1113

HGNC: 1113

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling