Rekombinanter WT1 Antikörper
Kurzübersicht für Rekombinanter WT1 Antikörper (ABIN7882700)
Target
Alle WT1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Recombinant Wilms Tumor 1 Antibody (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant human protein was used as the immunogen for the recombinant Wilms Tumor 1 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
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Titering of the recombinant Wilms Tumor 1 antibody may be required for optimal performance.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the recombinant Wilms Tumor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- WT1 (Wilms Tumor 1 (WT1))
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Andere Bezeichnung
- Wilms Tumor 1
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Hintergrund
- Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]
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UniProt
- P19544
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Pathways
- Tube Formation
Target
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