UCP3 Antikörper

Produktnummer ABIN7882641

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UCP3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für UCP3 Antikörper (ABIN7882641)

Target: UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UCP3 Antikörper

Verwendungszweck: UCP3 Antibody / SLC25A9

Sequenz: LDTAKVRLQI QGENQAVQTA RLVQYR

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids LDTAKVRLQIQGENQAVQTARLVQYR were used as the immunogen for the UCP3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the UCP3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the UCP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu UCP3

Target: UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

Andere Bezeichnung: UCP3

Hintergrund: Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.

UniProt: P55916

Pathways: Proton Transport