SIRT4 Antikörper

Produktnummer ABIN7882276

Der Kaninchen Polyklonal anti-SIRT4 Antikörper wird verwendet zum Nachweis von SIRT4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC (p).

Kurzübersicht für SIRT4 Antikörper (ABIN7882276)

Target: SIRT4 (Sirtuin 4 (SIRT4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SIRT4 Antikörper

Verwendungszweck: SIRT4 Antibody

Sequenz: HLKPDVVFFG DTVNPDKVDF VHKRVKEAD

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids HLKPDVVFFGDTVNPDKVDFVHKRVKEAD from the human protein were used as the immunogen for the SIRT4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SIRT4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SIRT4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Andere Bezeichnung: SIRT4

Hintergrund: Sirtuin 4, also known as SIRT4, is a protein which in humans is encoded by the SIRT4 gene. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion