PDHB Antikörper

Produktnummer ABIN7882117

Der Kaninchen Monoklonal anti-PDHB Antikörper wird verwendet zum Nachweis von PDHB in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für PDHB Antikörper (ABIN7882117)

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AEAD-16

Produktdetails anti-PDHB Antikörper

Verwendungszweck: PDHB Antibody / Pyruvate Dehydrogenase E1 beta subunit

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Pyruvate Dehydrogenase E1 beta subunit / PDHB was used as the immunogen for the PDHB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDHB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the PDHB antibody at -20oC.

Details zu PDHB

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Andere Bezeichnung: PDHB

Hintergrund: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. [RefSeq]

UniProt: P11177

Pathways: Warburg Effekt