PRC1 Antikörper

Produktnummer ABIN7882088

Der Kaninchen Monoklonal anti-PRC1 Antikörper (Klon EH-16) (ABIN7882088) detektiert spezifisch PRC1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PRC1 Antikörper (ABIN7882088)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: EH-16

Produktdetails anti-PRC1 Antikörper

Verwendungszweck: PRC1 Antibody

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human PRC1 was used as the immunogen for the PRC1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PRC1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the PRC1 antibody at -20oC.

Details zu PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Andere Bezeichnung: PRC1

Hintergrund: Protein regulator of cytokinesis 1 (PRC1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression. [UniProt]

UniProt: O43663