PRC1 Antikörper (pThr481)

Produktnummer ABIN7230766

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRC1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PRC1 Antikörper (pThr481) (ABIN7230766)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PRC1 Antikörper

Bindungsspezifität: pThr481

Verwendungszweck: Rabbit Anti-PRC1 (Phospho-Thr481) Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PRC1Phospho occurs at Thr481

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PRC1 (Phospho-Thr481) Polyclonal Antibody protein at AA range: 481

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Andere Bezeichnung: PRC1

Hintergrund: Protein regulator of cytokinesis 1PRC1 encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. PRC1 (Protein Regulator Of Cytokinesis 1) is a Protein Coding gene. Among its related pathways are Semaphorin interactions and Cytoskeletal Signaling.

Molekulargewicht: 72kD

Gen-ID: 9055

UniProt: O43663