Rekombinanter Podoplanin Antikörper

Produktnummer ABIN7881986

Der Kaninchen Monoklonal anti-Podoplanin Antikörper (Klon PDPN-8950R) (ABIN7881986) detektiert spezifisch Podoplanin in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Podoplanin Antikörper (ABIN7881986)

Target: Podoplanin (PDPN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: PDPN-8950R

Produktdetails anti-Podoplanin Antikörper

Verwendungszweck: Podoplanin Antibody / PA2.26 antigen / Gp36 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human PDPN protein was used as the immunogen for the Podoplanin antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Podoplanin

Hintergrund: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport