Nuclear Antigen Antikörper

Produktnummer ABIN7881829

Der Maus Monoklonal anti-Nuclear Antigen Antikörper wird verwendet zum Nachweis von Nuclear Antigen in Proben von Human, Maus und Ratte. Er wurde validiert für IHC (p).

Kurzübersicht für Nuclear Antigen Antikörper (ABIN7881829)

Target: Nuclear Antigen (IPO-38)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Nuclear Antigen Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SPM515

Produktdetails anti-Nuclear Antigen Antikörper

Verwendungszweck: IPO38 Antibody (Proliferation Marker)

Aufreinigung: PEG precipitation

Immunogen: Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO38 antibody.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IPO38 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the IPO38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Nuclear Antigen

Target: Nuclear Antigen (IPO-38)

Andere Bezeichnung: IPO38

Hintergrund: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.