Nuclear Antigen Antikörper

Produktnummer ABIN3025764

Der Maus Monoklonal anti-Nuclear Antigen Antikörper wird verwendet zum Nachweis von Nuclear Antigen in Proben von Human, Maus und Ratte. Er wurde validiert für IHC (p).

Kurzübersicht für Nuclear Antigen Antikörper (ABIN3025764)

Target: Nuclear Antigen (IPO-38)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Nuclear Antigen Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IPO-38

Produktdetails anti-Nuclear Antigen Antikörper

Verwendungszweck: IPO-38 Antibody (Proliferation Marker) (azide and preservative free)

Aufreinigung: PEG precipitation

Immunogen: Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO-38 antibody.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IPO-38 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the IPO-38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Nuclear Antigen

Target: Nuclear Antigen (IPO-38)

Andere Bezeichnung: IPO-38

Hintergrund: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO38 may be a useful marker of cell proliferation during monitoring of tumor progression.