Rekombinanter Nkx2-2 Antikörper

Produktnummer ABIN7881815

Der Kaninchen Monoklonal anti-Nkx2-2 Antikörper (Klon RMNK2-1) (ABIN7881815) detektiert spezifisch Nkx2-2 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Nkx2-2 Antikörper (ABIN7881815)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RMNK2-1

Produktdetails anti-Nkx2-2 Antikörper

Verwendungszweck: Recombinant NKX2.2 Antibody / Rabbit Monoclonal

Aufreinigung: Protein A affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the recombinant NKX2.2 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: NKX2.2

Hintergrund: NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]

Pathways: Dopaminergic Neurogenesis