Rekombinanter Myosin VIIA Antikörper

Produktnummer ABIN7881738

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Myosin VIIA in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter Myosin VIIA Antikörper (ABIN7881738)

Target: Myosin VIIA (MYO7A)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Myosin VIIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AFCH-13

Produktdetails anti-Myosin VIIA Antikörper

Verwendungszweck: MYO7A Antibody / Unconventional Myosin-VIIa

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to Unconventional Myosin-VIIa was used as the immunogen for the MYO7A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MYO7A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MYO7A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Myosin VIIA

Target: Myosin VIIA (MYO7A)

Andere Bezeichnung: MYO7A

Hintergrund: Unconventional Myosin-VIIa (MYO7A) is an actin-based motor protein involved in intracellular transport and structural organization within sensory cells. It plays a critical role in the function of hair cells in the inner ear and photoreceptor cells in the retina, contributing to mechanosensory and visual processes.

Mutations in MYO7A are associated with hereditary hearing loss, Usher syndrome type 1B, and certain forms of retinitis pigmentosa. MYO7A is essential for maintaining stereocilia structure in cochlear hair cells and for transporting opsin-containing vesicles in retinal cells, highlighting its importance in sensory cell maintenance and signaling.

Using a high-quality MYO7A antibody enables sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An MYO7A antibody from NSJ Bioreagents provides consistent performance for research into sensory biology, genetic disorders, and intracellular transport mechanisms. Selecting the right MYO7A antibody is essential for achieving accurate and reproducible results.

UniProt: Q13402

Pathways: Sensory Perception of Sound