Myosin VIIA Antikörper (AA 830-910)

Produktnummer ABIN7229866

Der Kaninchen Polyklonal anti-Myosin VIIA Antikörper wird verwendet zum Nachweis von Myosin VIIA in Proben von Human und Maus. Er wurde validiert für ELISA und WB.

Kurzübersicht für Myosin VIIA Antikörper (AA 830-910) (ABIN7229866)

Target: Myosin VIIA (MYO7A)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin VIIA Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Myosin VIIA Antikörper

Bindungsspezifität: AA 830-910

Verwendungszweck: Rabbit Anti-MYO7A Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MYO7A protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYO7A protein at AA range: 830-910

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Myosin VIIA

Target: Myosin VIIA (MYO7A)

Andere Bezeichnung: MYO7A

Hintergrund: Unconventional myosin-VIIaMYO7A (Myosin VIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in MYO7A are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 243kD

Gen-ID: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound