MAP4K3 Antikörper

Produktnummer ABIN7881655

Der Maus Monoklonal anti-MAP4K3 Antikörper wird verwendet zum Nachweis von MAP4K3 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für MAP4K3 Antikörper (ABIN7881655)

Target: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP4K3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 219CT8-3-1

Produktdetails anti-MAP4K3 Antikörper

Verwendungszweck: MAP4K3 Antibody / MEKKK3 / GLK

Aufreinigung: Purified

Immunogen: Recombinant human protein was used as the immunogen for the MAP4K3 antibody.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the MAP4K3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot the MAP4K3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MAP4K3

Target: MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))

Andere Bezeichnung: MAP4K3

Hintergrund: This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

UniProt: Q8IVH8

Pathways: MAPK Signalweg