Lamin A/C Antikörper

Produktnummer ABIN7881457

Der Maus Monoklonal anti-Lamin A/C Antikörper wird verwendet zum Nachweis von Lamin A/C in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für Lamin A/C Antikörper (ABIN7881457)

Target: Lamin A/C (LMNA)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lamin A/C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1073CT3-1-3

Produktdetails anti-Lamin A/C Antikörper

Verwendungszweck: Lamin A/C Antibody

Aufreinigung: Protein G purified

Immunogen: Recombinant human LMNA was used as the immunogen for the Lamin A/C antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Lamin A/C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the LMNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Lamin A/C

Target: Lamin A/C (LMNA)

Andere Bezeichnung: Lamin A/C

Hintergrund: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone. [UniProt]

UniProt: P02545

Pathways: Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus