Rekombinanter Iba1 Antikörper

Produktnummer ABIN7881325

Der Kaninchen Monoklonal anti-Iba1 Antikörper wird verwendet zum Nachweis von Iba1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Rekombinanter Iba1 Antikörper (ABIN7881325)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Iba1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AFGH-1

Produktdetails anti-Iba1 Antikörper

Verwendungszweck: AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to Allograft inflammatory factor 1 was used as the immunogen for the AIF-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AIF-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the AIF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Andere Bezeichnung: AIF-1

Hintergrund: Allograft inflammatory factor 1 (AIF-1) is a cytoplasmic, calcium-binding protein predominantly expressed in activated macrophages and microglia. It is involved in the regulation of immune and inflammatory responses, contributing to cell proliferation, migration, and cytokine production. AIF-1 plays roles in vascular pathology, tissue repair, and immune-mediated diseases.

Elevated expression of AIF-1 has been associated with various pathological conditions, including atherosclerosis, autoimmune disorders, and neuroinflammation. It serves as a marker for activated immune cells, making it valuable for studying inflammation-related mechanisms and disease progression.

Using a high-quality AIF-1 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An AIF-1 antibody from NSJ Bioreagents provides reliable performance for research in immunology, neurobiology, and cardiovascular disease. Selecting the right AIF-1 antibody ensures accurate and reproducible experimental outcomes.

UniProt: P55008

Pathways: Smooth Muscle Cell Migration