Rekombinanter IL7R Antikörper

Produktnummer ABIN7881317

Der Kaninchen Monoklonal anti-IL7R Antikörper (Klon 22I71) (ABIN7881317) detektiert spezifisch IL7R in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter IL7R Antikörper (ABIN7881317)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IL7R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 22I71

Produktdetails anti-IL7R Antikörper

Verwendungszweck: IL7RA Antibody / Interleukin-7 receptor alpha / CD127

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to Interleukin-7 receptor alpha was used as the immunogen for the IL7RA antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL7RA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IL7RA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: IL7RA

Hintergrund: Interleukin-7 receptor alpha (IL7RA) is a type I transmembrane glycoprotein that forms part of the receptor complex for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP). It plays a crucial role in lymphocyte development, survival, and homeostasis, particularly in T-cell and B-cell biology.

Genetic variations in IL7RA have been associated with susceptibility to autoimmune diseases, such as multiple sclerosis and type 1 diabetes, as well as immune deficiency disorders. IL7RA signaling regulates lymphocyte proliferation, differentiation, and maintenance, making it a valuable focus for immunological and therapeutic research.

Using a high-quality IL7RA antibody enables accurate detection of the protein in applications including western blot, immunohistochemistry, and flow cytometry. An IL7RA antibody from NSJ Bioreagents delivers consistent and reproducible performance for studies on immune signaling, lymphocyte biology, and disease pathogenesis. Selecting the right IL7RA antibody ensures reliable results in both basic research and clinical investigations.

UniProt: P16871

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size