IL-25 Antikörper

Produktnummer ABIN7881298

Der Maus Monoklonal anti-IL-25 Antikörper wird verwendet zum Nachweis von IL-25 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für IL-25 Antikörper (ABIN7881298)

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-25 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IL25-625

Produktdetails anti-IL-25 Antikörper

Verwendungszweck: IL-25 Antibody / IL-17E (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant protein fragment was used as the immunogen for the IL-25 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL-25 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL-25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL-25

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Andere Bezeichnung: IL-25

Hintergrund: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.

UniProt: Q9H293