IFNA1 Antikörper

Produktnummer ABIN7881253

Der Maus Monoklonal anti-IFNA1 Antikörper (Klon 2-48) (ABIN7881253) detektiert spezifisch IFNA1 in WB, FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IFNA1 Antikörper (ABIN7881253)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 2-48

Produktdetails anti-IFNA1 Antikörper

Verwendungszweck: IFNA1 Antibody / Interferon alpha 1

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IFNA1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: IFNA1

Hintergrund: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C