IFNA1
Reaktivität: Human
ELISA
Wirt: Maus
Monoclonal
unconjugated
Applikationshinweise
Optimal dilution of the IFNA1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
IFNA1
(Interferon, alpha 1 (IFNA1))
Andere Bezeichnung
IFNA1
Hintergrund
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.