EIF4E Antikörper
Kurzübersicht für EIF4E Antikörper (ABIN7880753)
Target
Alle EIF4E Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- EIF4E Antibody
-
Aufreinigung
- Affinity purified
-
Immunogen
- A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the EIF4E antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store the EIF4E antibody at -20oC.
-
-
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
-
Andere Bezeichnung
- EIF4E
-
Hintergrund
- EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
-
UniProt
- P06730
-
Pathways
- BCR Signaling
Target
-